91吃瓜

庞瑞萍，91吃瓜 教授，博士生导师。主要研究方向为消化系统免疫炎症相关性疾病的发病机制，脑-肠互作异常相关疾病等。主持国家自然科学基金项目三项，广东省自然科学基金项目四项，参与国家自然科学基金-广东省联合重点项目、省部级科研项目若干。

近年来发表的主要学术论著

1. Fei-Ran Zhang, Jie Tang, Ying Lai, Shi-Qi Mo, Zhuo-Miao Lin, Qing-Qing Lei, Cong-Cong Han,| An-Dong Zhou, Xiao-Fei Lv, Cheng Wang, Jing-Song Ou, Jia-Guo Zhou*, Rui-Ping Pang*. Smooth muscle cell Piezo1 is essential for phenotypic switch and neointimal hyperplasia. Br J Pharmacol. 2025.
2. Ge F, Sun Y, Han CC, Wei ZL, Guan X, Guo SW, Quan S, Zhou JG, Pang RP*. Plasma Glutaminyl-Peptide Cyclotransferase Mediates Glucosamine-Metabolism-Driven Protection Against Hypertension: A Mendelian Randomization Study. Int J Mol Sci. 2024.
3. Yang J, Xie MX, Hu L, Wang XF, Mai JZ, Li YY, Wu N, Zhang C, Li J, Pang RP*, Liu XG*. Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury. Brain Behav Immun. , 2018.
4. Man-Xiu Xie#, Rui-Ping Pang#, Jie Yang, Kai-Feng Shen, Jing Xu, Xiong-Xiong Zhong, Shao-Kun Wang, Xiao-Long Zhang, Yan-Qing Liu, Xian-Guo Liu，Bulleyaconitine A preferably reduces tetrodotoxinsensitivesodium current in uninjured dorsal root ganglion neurons of neuropathic rats probably via inhibition of protein kinase C. Pain, 2017.
5. Rui-Ping Pang*, Man-Xiu Xie, Jie Yang, Kai-Feng Shen, Xi Chen, Ying-Xue Su, Chao Yang, Jing Tao, Si-Jia Liang, Jia-Guo Zhou, He-Quan Zhu, Xu-Hong Wei, Yong-Yong Li, Zhi-Hai Qin, Xian-Guo Liu, Downregulation of ClC-3 in dorsal root ganglia neurons contributes to mechanical hypersensitivity following peripheral nerve injury. Neuropharmacology, 2016 .
6. Lin-Yan Huang, Qing He, Si-Jia Liang, Ying-Xue Su, Li-Xiong Xiong, Qian-Qian Wu, Qin-Yan Wu, Jing Tao, Jian-Ping Wang, Yong-Bo Tang, Xiao-Fei Lv, Jie Liu, Yong-Yuan Guan, Rui-Ping Pang*, Jia-Guo Zhou*, ClC-3 chloride channel/antiporter defect contributes to inflammatory bowel disease in humans and mice, Gut, 2014.
7. Kai-Feng Shen, He-Quan Zhu, Xu-Hong Wei, Jun Wang, Yong-Yong Li, Rui-Ping Pang*, Xian-Guo Liu*，Interleukin-10 down-regulates voltage gated sodium channels in rat dorsal root ganglion neurons. Experimental Neurology，2013.
8. Xi Chen#, Rui-Ping Pang#, Kai-Feng Shen , Manfred Zimmermann, Wen-Jun Xin,Yong-Yong Li , Xian-Guo Liu ,TNF-α enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury.  Experimental Neurology，2011 

9. Xian-Guo Liu, Rui-Ping Pang , Li-Jun Zhou , Xu-Hong Wei , and Ying Zang，Chapter 5 Neuropathic Pain: Sensory Nerve Injury or Motor Nerve Injury? Translational Research in Pain and Itch, Advances in Experimental Medicine and Biology. 2016.

   科研项目

   1. 国家自然科学基金面上项目，敲除单核细胞机械力敏感性离子通道Piezo1促进炎症性肠病发生及机制研究，55万元，2022-2025

   2. 广东省自然科学基金面上项目，肠上皮细胞Piezo1在肠易激综合征中的作用及机制研究，15万元，2024-2026

   3. 广东省自然科学基金面上项目，单核细胞Piezo1机械敏感性离子通道调控炎症性肠病发生及机制，10万元，2022-2024

   4. 广东省自然科学基金面上项目，容积敏感性氯通道SWELL1调控小胶质细胞活化参与神经病理性疼痛及机制研究，10万元，2019-2022

   5. 国家自然科学基金面上项目，ClC-3下调导致DRG神经元兴奋性增高和机械痛敏的机制研究，70万元，2015-2018